Novel anti-viral strategies against bioterrorist agents. (Quantum Medicine Update).


Townsend Letter for Doctors and Patients; 2/1/2002; Yanick, Paul Jr.

Terrorists have been experimenting with engineered viruses that will not respond to medical treatment or vaccinations. Daunting technical obstacles stand in the way of utilizing alternative methods to enhance the immune system against bioterrorist agents.

New insights gleaned from the human genome and from anti-viral research conducted by the pharmaceutical industry have been nothing short of breathtaking. Despite these advances, drug researchers admit to one serious flaw in the clinical potential of their findings: viruses develop drug resistance or insensitivity to treatment and can mutate at lightning speed so that drugs quickly fail to provide effective long-term treatment and immune protection. (1-6)

To combat novel viral strains, we must understand thoroughly the mechanisms that viruses use to gain entrance to target sites in the body as well as the strategies that the host uses to prevent them from doing so. Clearly advanced anti-viral research of pharmaceutical companies may provide additional clues into how to target anti-infective agents at viral infections on multiple levels, instead of aiming treatment at a single phase of viral activity.

Innovative immunomodulation and re-modulation with host defense potentiators and immune potentiators have been presented by the author to augment the body's army of immune cells that identify, tag, poison, blast, and consume microbes that invade the body's biological terrain. However, when these anti-viral approaches are employed, it is necessary for the clinician to understand the extraordinary complexity of the immune system at the quantum level as it stores information, and establishes communication with the entire organism faster than the speed of light. Ideally, anti-viral strategies should be designed to enhance the immune system's ability to patrol, enforce, and attack invading microbes with greater efficiency or operational complexity by re-establishing quantum coherence.

The International Institute of Biophysics, composed of 15 groups of scientists from university research centers around the world, defines "quantum coherence" as the highest level of order or organization within the human organism. According to their research, healthy individuals have exquisite coherence at the quantum level while sick individuals with weak immune systems or cancer have chaotic, poor coherence with disturbed biophoton cellular biocommunicatiOn.

Understanding New and Powerful Virus-fighting Strategies

Designing anti-viral strategies is not extremely difficult because all viruses use similar strategies to identify and lock onto their particular prey, replicate, and then exit the cell to infect other cells. Once a virus is able to attach to a receptor on the cell membrane, it can penetrate the cell. Because viruses take advantage of deficient cell membranes and/or oxidative stress to enter the cell, correcting phospholipid and essential fatty acid deficiencies while maintaining cellular redox potential is an important step in any immune enhancement program. Moreover, it is absolutely essential that the virally-infected patient completely eliminates trans fatty acids (margarines, processed cooking oils, and genetically-modified oils such as canola oil) because viruses thrive and seem to penetrate deeper into the lymphatic system channels when these fats are in the daily diet.

Once in the cytoplasm of the cell, the virus uncoats or discards its lipid or protein shell. Then, it effectively hijacks the cell's genetic material, makes a DNA copy of its own genome which it then inserts into the host cell's DNA. It's important to note that the cell-to-cell spread of the virus can be prevented or stalled by augmenting immune responses with appropriate combinations of host defense potentiators and immune potentiators. However, all phases of viral infection must be targeted for optimal results. The overwhelming majority of natural immune enhancement approaches fail to prevent the viral entry into the cell and the viral hijacking of the cell's unstable genes. They also fall to consider the critical role of quantum coherence in their approaches. Effective immunomodualtion therapies must be multidirectional and fully preserve all immune responses in order to subdue and conquer viral invaders and speed the organism's recovery from viral infection.

Because viruses use the same basic mechanisms for subjugating cells (this can vary slightly depending on the type of genome the virus possesses), they can crank out copies of viral DNA at incredible speeds in the nucleus of the cell. Whatever the type of genome, a virus, is capable of producing millions of new viral particles with the aid of the cell's raw material and machinery. While some viruses act only at their point of entry (adenoviruses, for example, invade the eye causing conjunctivitis), others move beyond their point of entry and spread through the lymphatic system, causing a generalized sub-clinical infection of many tissues of the body that later erupts into a full blown infection when stress overwhelms the body. Hence, effective anti-viral agents must be able to penetrate into the lymphatic system where lymph node and other immune centers of activity are allowed to function with greater operational complexity and strength.

New Clinical Insights into Novel Viral Infections

Recently, I reported a new herpes-type viral infection in patients that appeared around the aftermath of the attack on America. (7) Many of our existing patients who lived in the vicinity of the World Trade Center area were infected with this virus (they were also exposed to arsenic, asbestos, and other toxic fumes for several months). Since the writing of the previous column, we now have a total of 60 cases who reported the same constellation of symptoms: headaches, nausea, acute and sharp stomach pain, upper neck and back pain (specifically of the rhomboids, levator scapulae, and trapezius muscles), and chronic fatigue. Since these patients were seen by our staff doctors many times before September 11th and never reported these symptoms, we surmised that they were most likely infected with the same virus (they all tested positive for herpes-type nosodes which appeared to be the primary immune system stressor in all these cases). This new or mutated virus presumably entered the body's neurons producing prog eny that migrated down the neuronal fibers into the stomach (there were no unsightly coldsores that are the usual result of tissue damage of the herpes virus). Why was this herpes strain so different? It didn't target the skin. Instead, it specifically targeted the stomach/duodenal linings causing ulcer-like pain, nausea, and pain in the muscles that are kinesiologically-associated with the stomach meridian.

Obviously, understanding the point of entry of a particular virus is critical to the success of immune enhancement strategies. In these cases, the tube-like fibers of the nervous system served as a hidden tunnel for these viruses, allowing them to travel throughout the body without being detected by immune surveillance. Although the causes of these viral infections remain obscure (they may be mutations and not bioterrorist agents), anti-viral strategies were developed to decrease these immune system stressors while simultaneously targeting the nervous system and stomach. This strategy resulted in patient relief in all cases within 7-10 days (many sought out conventional medical treatment but did not respond to the medicine prescribed).

It is important to remember that viruses are basically a packaged set of genes. They must invade living cells in order to replicate and do damage to the host organism. Natural compounds were combined in an attempt to bar viral entry into the cells, jam the copier to halt viral replication, improve DNA coherence and stability, and stop viral traffic and the spread of infection throughout the body. Special attention was directed to the selective uptake by the various tissues of the body for phytochemicals and fermented mycelial extracts. The clinical goal was to target and strengthen specific organs or glands of the body, reduce immune system stressors and target the neurons with special fermented extracts of medicinal mushrooms. (8-12) Immunomodulation therapies can be designed to provide antiviral strategies that capitalize on the immune system's vastly superior qualities. These strategies are virtually non-existent in mainstream medicine or alternative health care because experts lack appreciation of the we b-like interaction and interpenetration of the immune system with all other systems of the body, especially the human energy system.

Despite these reductionalistic tendencies, excellent research has provided us with bits and pieces of the anti-viral puzzle. Viral genomics has spurned exciting research into novel anti-viral compounds that target a specific phase of viral infection. Let's examine some of the major highlights of this research:

1. Medium chain fatty acids (MCFAs) -- Ingesting MCFAs can reduce viral load by 50% in some studies by uncoating lipid-enveloped viruses before they enter cells. (13-16)

2. Viscum Album -- rich in glycoproteins, polypeptides, lignans and triterpenes, viscum album has the unique ability to stabilize genetic mechanisms at the quantum level (all the interactions of the immune system are orchestrated by biophotons and chemical signals and responses), resulting in quantum coherence. (17-18)

3. Larrea tridentata -- scientific studies have documented the powerful anti-viral activity of this unique and powerful plant including its unique ability to cleanse and detoxify the lymphatic system of viral infections. (19-20)

4. Fermented Mycelial extracts of Hericium erinaceous, Grifoia frondosa, Reishi, Ganoderma lucidum, and Cordyceps sinensis -- for effective immune enhancement and bioregulation against viral infection. Our research has found that the most effective mycelial extracts are produced by fermenting the mycelia part of the mushrooms that are combined with tissue and organ specific phytonutrients (results were not achieved with whole mushroom powder or fermentations of the entire mushroom without the use of appropriate plant fiavonoids) (8,12,21-22)

The complex interactions and power of the immune system are orchestrated by biophoton and chemical events. The awesome intelligence and organization of the immune system and its counterparts is made possible by quantum coherence. Achieving quantum coherence is the primary goal in enhancing the immune system against potential viral threats. Like a conductor bringing each individual instrument into a beautiful, collective sound in a large orchestra, biophotons work individually and harmonize together to achieve quantum coherence. Again, the better the coherence between these communication events in the sub-molecular world of cells, the greater power the immune system has in preventing and counteracting viral overload. When quantum coherence is reestablished at the genetic level, the immune response may be so fast and effective that the person may not even be aware of a viral invasion. With the threat of bioterrorism before us, reestablishing quantum coherence while using multidirectional immunomodulation techn iques may result in increasing survival rates against some of the world's deadliest viruses. More research is needed to document these theoretical ideas and clinical insights.

In conclusion, immunomodulation therapies are highly effective when organ/gland and cell specificity is employed to boost host defense. Since nutritional deficiencies allow viruses to enter cells and trigger viral mutations, they must be identified and corrected without delay. The ability of viruses to wreak havoc should not be underestimated: between 1918 and 1919, the "Spanish" flu killed 20 million people.

New molecular technologies are helpful in understanding new generations of viruses and in developing new strategies to outwit deadly forms of new viruses. Since viruses swap genes or parts of their genes, new viruses are constantly emerging and can evolve into a form the immune system cannot recognize. Hence, viral mutations and/or genetically-engineered superbugs may pose serious and even lethal threats to the human body. Emerging anti-viral strategies are now available to reduce the stress load on the immune system and move the immune system into a stronger and more powerful defense against viral infections.

References

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(2.) Ploegh, Hidde. Viral Strategies of Immune Evasion, Science, 1998, Vol 280:5361, 248-253.

(3.) Jones, Philip S. Strategies for Antiviral Drug Discovery, Antiviral Chemistry and Chemotherapy, 1998, 9:4,283-302.

(4.) Bernstein, Jack M. Antiviral Chemotherapy: General Overview. 2000: Wright State University School of Medicine, Division of Infectious Diseases.

(5.) Page, Roderic D. M. and Holmes, Edward C., Molecular Evolution, 1988, Blackwell Science.

(6.) Collier, Leslie and Oxford, John, Human Virology, 2000, Oxford University Press.

(7.) Yanick, P Immune System Protection against Bioterrorism. Dec 2001. Townsend Letter for Doctors & Patients.

(8.) Cody, V et al. Plant Flavonoids in Biology and Medicine. Biochemical, Cellular, and Molecular Properties 1988; Alan R. Liss; New York.

(9.) Yanick P. Meridian/Organ Nutraceutic Resonant Complexes: New Hope for Chronically-Sick Individuals. 2000, May Townsend Letter for Doctors & Patients; 136-39.

(10.) Yanick, P. Boosting Nutrient Uptake in Chronic Illness, Dec 2000, Townsend Letter for Doctors & Patients.

(11.) Yanick, P. Food Supplement Benefits and Risks in Carcinogenesis: Part I, Oct 2001, Townsend Letter for Doctors & Patients.

(12.) Borchers, AT et al. Mushrooms, tumors, and immunity Proceedings of the Society of Experimental Biological Medicine, 1999, 4:282-93.

(13.) Kabara JJ, Swieczkowski DM, Conley AJ and Truant JP: Fatty Acids and Derivatives as Antimicrobial Agents. 1992; Antimicrobial Agents and Chemotherapy, 1972; 23-28.

(14.) Kabara JJ: Toxicological, Bacteriocidal and Fungicidal Properties of Fatty Acids and Some Derivaitives JAOCS 56:760, 1979.

(15.) Hierholzer JC and Kabra JJ: In vitro effects of monolaurin compounds on enveloped RNA and DNA viruses. J. Food Safety 4:1-12, 1982.

(16.) Enig, MG: Coconut Oil: An Anti-bacterial, Anti-viral Ingredient for Food, Nutrition and Health. 1997, AVOC Luric Symposium. Manila, Philippines.

(17.) McTaggert, L The Field: the Quest for the Secret Force of the Universe, 2001, Harper Collins.

(18.) Popp, AF. Biophotonen. Schriftenreihe Krebsgeschehen Bd 6,2, Aulf VIM, 1984, Heidelberg.

(19.) M Angeles Verastegui et al Antimicrobial activity of Extracts of three major plants of the Chichuahuan Desert. J of Enthopharmacology, 52, 1996, 175-77.

(20.) Brinker F Larrea tridentata, British J of Phytotherapy, 3:1, 1994, 10-30.

(21.) Kawagishi, H. et al: Herinacines A,B,C, strong stimulators of nerve growth factor from the mushroom Hericium. Tetrahedron Letters, 1991;32:35 4561-64.

(22.) Kawagishi, H. et al: Herinacines A,B,C, strong stimulators of nerve growth factor from the mushroom Hericiuin. Tetrahedron Letters, 1994;35:10, 1569-72.

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